A case of intraorbital malignant lymphoma biopsied using an endoscopic transnasal approach.

Background: While most orbital tumors are primary, some are secondary, including extension or invasion from adjacent sites. The diagnosis varies widely, and the treatment strategy depends on the pathological diagnosis. Transcranial and transorbital surgical approaches are typically used. Recently, a transnasal endoscopic approach has emerged as a viable option. We report a case of an intraorbital tumor treated with endoscopic transnasal biopsy and compare the results with those of other surgical approaches. Case Description: A 74-year-old woman visited a nearby hospital due to a right eye protrusion and decreased visual acuity. An intraorbital tumor was detected and the patient was referred to our hospital. Head computed tomography revealed a mass along the posterior wall of the right orbital apex. Contrast-enhanced magnetic resonance imaging showed a 37-mm lesion with a uniform contrast effect and no intracranial extension. Intraorbital lymphoma was considered a differential diagnosis, and a biopsy was performed using an endoscopic transnasal approach. The pathological diagnosis was B-cell lymphoma, and chemotherapy was administered. Conclusion: The endoscopic transnasal approach for intraorbital tumors is less invasive, highly cosmetic, and useful, especially for medial and inferior orbital lesions.

Cerebral tumor embolism from thyroid cancer treated by mechanical thrombectomy: illustrative case.

BACKGROUND: Development in mechanical thrombectomy is progressing dramatically. Tumor embolism has been rarely reported on the basis of pathological study of the retrieved thrombus. Herein, the authors report a case of cerebral tumor embolism from advanced thyroid cancer, which was successfully treated with mechanical thrombectomy. OBSERVATIONS: A 57-year-old man was diagnosed with thyroid cancer with multiple lung metastases and chemotherapy was planned. He experienced left hemiparesis and was bought to the emergency section of the authors' hospital. Magnetic resonance angiography revealed right internal carotid artery occlusion and endovascular treatment was performed. Using a combination of aspiration catheter and stent retriever, white jelly-like embolus was retrieved. The pathological study demonstrated thyroid cancer embolism. Pulmonary vein invasion following lung metastasis of thyroid cancer was most presumably the cause of the tumor embolism. LESSONS: Lung metastasis invading the pulmonary vein may be a cause of tumor embolism. Mechanical thrombectomy using a combination of stent retriever and aspiration catheter is effective in removing the tumor embolus and the pathological examination of the embolus is essential.

Metastatic Brain Tumor in the Cerebellopontine Angle from Gastric Cancer: A Case Report.

Cerebellopontine angle (CPA) tumors are a common type of benign tumors, which are similar to vestibular schwannomas; however, the incidence of CPA metastasis is rare. Moreover, brain metastasis from gastric tumors is a rare occurrence, with an incidence of less than 1% in clinical cases. In this study, we report the case of a 71-year-old man who was admitted to our hospital with symptoms of nausea and gait instability for the past 1 week. He had no remarkable medical history. Magnetic resonance imaging revealed a tumor in the left CPA. Intraoperative diagnosis indicated the presence of metastatic papillary carcinoma. Postoperatively, gastric endoscopy revealed a protruding mass on the cardia of the stomach, which was histopathologically similar to that of the resected brain tumor. The patient underwent adjuvant cyberknife radiotherapy and chemotherapy. A prompt biopsy of the brain tumor is essential if any findings suggest malignancy.

Idiopathic Middle Meningeal Arteriovenous Fistula Associated with Segmental Arterial Mediolysis: A Case Report.

Objective: Middle meningeal arteriovenous fistula (MMAVF) is typically post-traumatic or iatrogenic in origin, but it can have an idiopathic origin in rare cases. Here, we report a case of idiopathic MMAVF complicated by segmental arterial mediolysis (SAM). Case Presentation: The patient was a 63-year-old woman admitted to our hospital with symptoms of right pulsating tinnitus for the past 2 months. She had no significant medical history. MRI and DSA revealed a right MMAVF. Selective embolization using coils was performed. Seven years later, when she underwent laparotomy for intestinal perforation, multiple aneurysms were found in the abdominal cavity. Left hemicolectomy was performed, and an aneurysm of the gastroepiploic artery was resected. Based on a pathological examination of the aneurysm, the patient was diagnosed with SAM. Coil embolization was performed to prevent rupture. Conclusion: This case report shows that MMAVF may be associated with SAM. Fistula embolization with coils is an effective treatment of MMAVF associated with SAM. Therefore, it is important to check for systemic diseases, such as SAM when idiopathic MMAVF is detected.

Takotsubo cardiomyopathy following mechanical thrombectomy for acute ischemic stroke: illustrative case.

BACKGROUND: Excess neurological stress by hemorrhagic stoke induces cardiomyopathy, namely takotsubo cardiomyopathy. Here, the authors report a case of takotsubo myopathy following mechanical thrombectomy for acute large vessel occlusion. OBSERVATIONS: A 73-year-old man was emergently brought to the authors' hospital because of left hemiparesis and consciousness disturbance. An ischemic lesion of the right cerebral hemisphere and the right internal carotid artery occlusion was revealed. Emergently, endovascular treatment was performed, and occlusion of the artery was reanalyzed. However, he suffered from hypotension with electrocardiogram abnormality. Subsequently, coronary angiography was performed, but the arteries were patent. The authors made a diagnosis of takotsubo cardiomyopathy. LESSONS: Endovascular recanalization for large cerebral artery occlusion is so effective that it is becoming widely used. Even in the successful recanalization, we need to care for the takotsubo cardiomyopathy.

Aggressive Intraoperative Cisternal Clot Removal After Clipping Aneurismal Subarachnoid Hemorrhage in Elderly Patients.

BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) in the elderly often has a poor prognosis even after surgical treatment in the acute phase. Additionally, subarachnoid clots are the strongest predictors of cerebral vasospasm and tend to be thicker and heavier due to cerebral atrophy. We aimed to compare the conventional surgical treatment in such patients and identify the independent predictors of a favorable outcome after aggressive surgical clot removal. METHODS: We included 40 patients with aSAH aged 70 or older. Each patient underwent aneurysmal clipping. We used the modified Rankin Scale to assess the primary outcome of neurologic status at discharge. We performed univariate analysis using the following factors: sex, age, neurologic, and general medical condition, radiographic data, aneurysm location, treatment approach, and timing of the aneurysm surgery. We divided the patients into irrigation and nonirrigation groups. We focused mainly on subarachnoid clots and analyzed them semiquantitatively using computed tomography. RESULTS: Clot removal was significantly greater in the irrigation group (n = 21) than in the nonirrigation group (n = 19). The period of intrathecal drainage was significantly shorter in the irrigation group (P = 0.002). The rate of occurrence of new low-density areas on CT scans was higher in the nonirrigation group. Outcomes were better in the irrigation group (P = 0.010). CONCLUSIONS: In elderly patients with aSAH in the acute phase, aggressive surgical clot removal after clipping showed favorable outcomes by facilitating early out-of-bed mobilization.